MGP-UWA-Sch of ChemBiochem-July 2015 071

Projects


Confirming the reference range for breastfeeding milk profile

Approximately 35% of all women who wean early report perceived insufficient milk as the primary reason, described as a woman perceiving that her supply is inadequate either to satisfy her infant’s hunger (based on the infant’s behavior, including the frequency and duration of breastfeeding sessions) or to support “adequate” weight gain. Individuals who perceive that they have insufficient milk are likely to use complementary bottles of infant formula, leading to a cycle of ever-decreasing breast milk production. Breastfeeding knowledge has been shown to be strongly correlated with breastfeeding confidence and actual lactation duration. Thus, evidence-based information can assist efforts to improve rates of successful breastfeeding by averting either unskilled or inconsistent professional support.
Measurement of milk supply by 24-hour in-home test-weighing of infants that can provide objective information that can support the confidence of breastfeeding mothers and their clinicians when breastfeeding parameters are shown to be normal. Alternatively, measurement can guide the clinician in the management and support of the breastfeeding dyad.
Interpretation of the results of the 24-hour milk profile depends on a well-defined reference range. The current reference range is based on data from 71 exclusively breastfeeding dyads. We aim to ensure the validity of the reference range by measuring a larger number of healthy breastfeeding dyads.

 


Measurement of improvement in milk supply following consultation with health professional

When a sub-optimal milk supply has been measured, the consulting clinician provides advice on strategies to increase milk production. Clinical indications of increased milk transfer during breastfeeding may be masked if supplementary feeds are given. Measurement of breastfeeding milk profile after clinical advice can provide an objective measure of the change in milk production and milk transfer.

 


An alternative method of measuring milk production and milk fat synthesis

Mothers may find that a full 24-hour period of test weighing is too difficult, e.g. if the infant wakes frequently at night. We have some results that suggest that using an electric breast pump to pump the breasts for 10 minutes at hourly intervals for 3 hours (4 pumps) will allow calculation of the average rate of milk synthesis and may also provide an accurate estimate of the rate of milk fat synthesis.

N.B. The milk that is expressed during pumping studies is collected in sterile containers and will be available to take home or feed during the stay.